Brief Description

CI-1040 is a selective MEK inhibitor (Ki = 300 nM in vitro). CI-1040 suppresses FGF-mediated angiogenesis in vivo and decreases VEGF expression. Enhances the therapeutic efficacy of taxol in vivo. Orally active.

Solubility

DMSO ≥92mg/mL; Water <1.2mg/mL; Ethanol ≥13mg/mL

Melting point

Boiling point

Density

Formula Weight:

Flash point

Storage conditions

Store at -20°C 2 years

Appearance:

White to off-white solid