Brief Description

COX-2 Inhibitor V, FK3311 is a cell-permeable and orally available sulfonanilide that acts as a selective Cox-2 inhibitor and NSAID. COX-2 Inhibitor V, FK3311 has been shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 μM in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung.

Solubility

DMSO

Melting point

Boiling point

Density

Formula Weight:

Flash point

Storage conditions

Store at -20°C 2 years

Appearance:

Light yellow to yellow solid