Brief Description

IM-12 is a potent GSK-3β inhibitor with IC50 of 53 nM; shows a significant activity in several biological tests which was comparable or even outplayed the effects of the known SB-216763.
IC50 value: 53 nM
Target: GSK-3β inhibitor
IM-12 acts as GSK-3b inhibitor resulting in the activation of downstream components of canonical Wnt signalling and has an adjacent positive impact on the neuronal differentiation in human neural progenitor cells.

Solubility

DMSO > 55 mg/ml

Melting point

Boiling point

Density

Formula Weight:

Flash point

Storage conditions

Store at -20°C 2 years

Appearance:

Light yellow to yellow solid